Bioproduction – Plant Protein Factories
Continuous Tobacco Trichome Protein Factory
PhylloTech utilizes a continuous plant expression system to produce proteins in glandular secreting trichomes of Nicotiana tabacum, specializing in difficult to produce proteins and antibodies that are cost sensitive. In this continuous trichome expression system, proteins are secreted to leaf surfaces where they can be easily recovered by simply washing leaves with an extraction buffer. This system eliminates the need for purification, significantly reduces the costs of production, and allows rapid scalability of target protein output to tens of thousands of plants. Key inputs are only light, water, and fertilizer, and plants can be grown efficiently and rapidly in a greenhouse or in the field using already existing farming methods. With this environmentally-friendly system, high amounts of purified proteins that are indistinguishable from native sources can be generated at low cost in a renewable manner
Maize Seed Protein Factories
From large scale protein production projects, PhylloTech utilizes novel chimeric maize seed promoters to create large amounts of seed specific proteins, enzymes and antibodies. From molecular biology, plant transformation, isolation planting and harvest, PhylloTech can complete all aspects of the project.
Biopesticide – Enzymes in Ag
PhylloTech’s core technology is based on our discovery that some plants secrete defensive proteins termed phylloplanins. This novel family of secreted plant proteins inhibit a broad range of agricultural pathogens. Our scientists have published reports on phylloplanin effectiveness and the results of their endeavors are clear: phylloplanins are extremely effective, broad-spectrum pathogen controls. We believe these antimicrobial proteins are the next generation of environmentally-friendly biofungicides and genetic crop traits to enhance disease resistance.
Quorum sensing is a biochemical process that allows bacterial populations to coordinate gene expression and plays a significant role in the onset of pathogenesis and biofilm development. Using Acylases, PhylloTech is currently developing environmentally-friendly methods to interrupt this process and limit the ability of bacterial pathogens to cause crop diseases.